×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

PDB 6r2e

PDB Information

PDB6R2E
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Evidence of Destabilization of the Human Thymidylate Synthase (hTS) Dimeric Structure Induced by the Interface Mutation Q62R.
Pozzi, C., Lopresti, L., Santucci, M., Costi, M.P., Mangani, S.
Biomolecules
HeaderTransferase
Released2019-03-16
Resolution2.550
CATH Insert Date14 Apr, 2019

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 14 Apr, 2019 Chopped
B 14 Apr, 2019 Chopped
C 14 Apr, 2019 Chopped
D 14 Apr, 2019 Chopped
E 14 Apr, 2019 Chopped
F 14 Apr, 2019 Chopped
G 14 Apr, 2019 Chopped
H 14 Apr, 2019 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
6r2eA00 15 Apr, 2019 3.30.572.10 Assigned
6r2eB00 15 Apr, 2019 3.30.572.10 Assigned
6r2eC00 15 Apr, 2019 3.30.572.10 Assigned
6r2eD00 15 Apr, 2019 3.30.572.10 Assigned
6r2eE00 15 Apr, 2019 3.30.572.10 Assigned
6r2eF00 15 Apr, 2019 3.30.572.10 Assigned
6r2eG00 15 Apr, 2019 3.30.572.10 Assigned
6r2eH00 15 Apr, 2019 3.30.572.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
CATH-Gene3D is a Global Biodata Core Resource Learn more...