PDB 6qu7

PDB Information

PDB6QU7
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies.
Christian, S., Merz, C., Evans, L., Gradl, S., Seidel, H., Friberg, A., Eheim, A., Lejeune, P., Brzezinka, K., Zimmermann, K., Ferrara, S., Meyer, H., Lesche, R., Stoeckigt, D., Bauser, M., Haegebarth, A., Sykes, D.B., Scadden, D.T., Losman, J.A., Janzer, A.
Leukemia
HeaderOxidoreductase
Released2019-02-26
Resolution1.520
CATH Insert Date16 Jun, 2019

PDB Images (2)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Jun, 2019 New

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q02127 PYRD_HUMAN Homo sapiens Dihydroorotate dehydrogenase (quinone), mitochondrial