PDB 6qmr

PDB Information

PDB6QMR
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway.
Karki, R.G., Powers, J., Mainolfi, N., Anderson, K., Belanger, D.B., Liu, D., Ji, N., Jendza, K., Gelin, C.F., Mac Sweeney, A., Solovay, C., Delgado, O., Crowley, M., Liao, S.M., Argikar, U.A., Flohr, S., La Bonte, L.R., Lorthiois, E.L., Vulpetti, A., Brown, A., Long, D., Prentiss, M., Gradoux, N., de Erkenez, A., Cumin, F., Adams, C., Jaffee, B., Mogi, M.
J.Med.Chem.
HeaderHydrolase
Released2019-02-08
Resolution2.000
CATH Insert Date28 Apr, 2019

PDB Images (19)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 28 Apr, 2019 Chopped
B 28 Apr, 2019 Chopped
C 28 Apr, 2019 Chopped
D 28 Apr, 2019 Chopped
E 28 Apr, 2019 Chopped
F 28 Apr, 2019 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
6qmrA01 29 Apr, 2019 2.40.10.10 Assigned
6qmrA02 29 Apr, 2019 2.40.10.10 Assigned
6qmrB01 29 Apr, 2019 2.40.10.10 Assigned
6qmrB02 29 Apr, 2019 2.40.10.10 Assigned
6qmrC01 29 Apr, 2019 2.40.10.10 Assigned
6qmrC02 29 Apr, 2019 2.40.10.10 Assigned
6qmrD01 29 Apr, 2019 2.40.10.10 Assigned
6qmrD02 29 Apr, 2019 2.40.10.10 Assigned
6qmrE01 29 Apr, 2019 2.40.10.10 Assigned
6qmrE02 29 Apr, 2019 2.40.10.10 Assigned
6qmrF01 29 Apr, 2019 2.40.10.10 Assigned
6qmrF02 29 Apr, 2019 2.40.10.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
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