PDB 6pet

PDB Information

PDB6PET
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of a C-8 hydroxychromene as a potent degrader of estrogen receptor alpha with improved rat oral exposure over GDC-0927.
Labadie, S.S., Li, J., Blake, R.A., Chang, J.H., Goodacre, S., Hartman, S.J., Liang, W., Kiefer, J.R., Kleinheinz, T., Lai, T., Liao, J., Ortwine, D.F., Mody, V., Ray, N.C., Roussel, F., Vinogradova, M., Yeap, S.K., Zhang, B., Zheng, X., Zbieg, J.R., Liang, J., Wang, X.
Bioorg.Med.Chem.Lett.
HeaderNuclear Protein
Released2019-06-20
Resolution2.200
CATH Insert Date04 Aug, 2019

PDB Images (5)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 04 Aug, 2019 New
B 04 Aug, 2019 New
C 04 Aug, 2019 New
D 04 Aug, 2019 New

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (0)

Accession Gene ID Taxon Description
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