PDB 6p8x

PDB Information

PDB6P8X
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Discovery ofN-(1-Acryloylazetidin-3-yl)-2-(1H-indol-1-yl)acetamides as Covalent Inhibitors of KRASG12C.
Shin, Y., Jeong, J.W., Wurz, R.P., Achanta, P., Arvedson, T., Bartberger, M.D., Campuzano, I.D.G., Fucini, R., Hansen, S.K., Ingersoll, J., Iwig, J.S., Lipford, J.R., Ma, V., Kopecky, D.J., McCarter, J., San Miguel, T., Mohr, C., Sabet, S., Saiki, A.Y., Sawayama, A., Sethofer, S., Tegley, C.M., Volak, L.P., Yang, K., Lanman, B.A., Erlanson, D.A., Cee, V.J.
Acs Med.Chem.Lett.
HeaderSignaling Protein/Inhibitor
Released2019-06-08
Resolution2.110
CATH Insert Date01 Sep, 2019

PDB Images (5)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 01 Sep, 2019 New
B 01 Sep, 2019 New
C 01 Sep, 2019 New
D 01 Sep, 2019 New

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (0)

Accession Gene ID Taxon Description