PDB Information

PDB6OJS
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceCryptosporidium hominis
Primary Citation
Understanding the structural basis of species selective, stereospecific inhibition for Cryptosporidium and human thymidylate synthase.
Czyzyk, D.J., Valhondo, M., Jorgensen, W.L., Anderson, K.S.
Febs Lett.
HeaderTransferase/Transferase Inhibitor
Released2019-04-12
Resolution3.210
CATH Insert Date23 Jun, 2019

PDB Images (6)

PDB Prints

PDB Chains (5)

Chain ID Date inserted into CATH CATH Status
A 23 Jun, 2019 New
B 23 Jun, 2019 New
C 23 Jun, 2019 New
D 23 Jun, 2019 New
E 23 Jun, 2019 New

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (5)

Accession Gene ID Taxon Description
A0A0S4TER9 A0A0S4TER9_CRYHO Cryptosporidium hominis Bifunctional dihydrofolate reductase-thymidylate synthase
A0A0S4TER9 A0A0S4TER9_CRYHO Cryptosporidium hominis Bifunctional dihydrofolate reductase-thymidylate synthase
A0A0S4TER9 A0A0S4TER9_CRYHO Cryptosporidium hominis Bifunctional dihydrofolate reductase-thymidylate synthase
A0A0S4TER9 A0A0S4TER9_CRYHO Cryptosporidium hominis Bifunctional dihydrofolate reductase-thymidylate synthase
A0A0S4TER9 A0A0S4TER9_CRYHO Cryptosporidium hominis Bifunctional dihydrofolate reductase-thymidylate synthase