PDB 6o3b

PDB Links
Overview

PDB Information

PDB	6O3B
Method	X-RAY DIFFRACTION
Host Organism	Homo sapiens
Gene Source	Homo sapiens
Primary Citation	Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies. Raman, S., Beilschmidt, M., To, M., Lin, K., Lui, F., Jmeian, Y., Ng, M., Fernandez, M., Fu, Y., Mascall, K., Duque, A., Wang, X., Pan, G., Angers, S., Moffat, J., Sidhu, S.S., Magram, J., Sinclair, A.M., Fransson, J., Julien, J.P. Proc. Natl. Acad. Sci. U.S.A.
Header	Signaling Protein
Released	2019-02-26
Resolution	2.500
CATH Insert Date	07 Apr, 2019

PDB Images (12)

Image of CATH 6o3b

6o3b

PDB 6o3b

Image of CATH 6o3bA

6o3bA

PDB Chain 6o3bA

Image of CATH 6o3bB

6o3bB

PDB Chain 6o3bB

Image of CATH 6o3bC

6o3bC

PDB Chain 6o3bC

Image of CATH 6o3bE

6o3bE

PDB Chain 6o3bE

Image of CATH 6o3bG

6o3bG

PDB Chain 6o3bG

Image of CATH 6o3bH

6o3bH

PDB Chain 6o3bH

Image of CATH 6o3bA01

6o3bA01

CATH Domain 6o3bA01

Image of CATH 6o3bA02

6o3bA02

CATH Domain 6o3bA02

Image of CATH 6o3bE01

6o3bE01

CATH Domain 6o3bE01

Image of CATH 6o3bE02

6o3bE02

CATH Domain 6o3bE02

Image of CATH 6o3bH00

6o3bH00

CATH Domain 6o3bH00

PDB Prints

PDB Chains (6)

Chain ID	Date inserted into CATH	CATH Status
A	07 Apr, 2019	Chopped
B	07 Apr, 2019	Holding pen
C	07 Apr, 2019	Holding pen
E	07 Apr, 2019	Chopped
G	07 Apr, 2019	Holding pen
H	07 Apr, 2019	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6o3bA01	08 Apr, 2019	2.60.40.10	Assigned
6o3bA02	08 Apr, 2019	2.60.40.10	Assigned
6o3bE01	08 Apr, 2019	2.60.40.10	Assigned
6o3bE02	08 Apr, 2019	2.60.40.10	Assigned
6o3bH00	08 Apr, 2019	1.10.2000.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O75084	FZD7_HUMAN	Homo sapiens	Frizzled-7
O75084	FZD7_HUMAN	Homo sapiens	Frizzled-7