PDB 6no9

PDB Information

PDB6NO9
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Optimization of Pan-Pim Kinase Activity and Oral Bioavailability Leading to Diaminopyrazole (GDC-0339) for the Treatment of Multiple Myeloma.
Wang, X., Blackaby, W., Allen, V., Chan, G.K.Y., Chang, J.H., Chiang, P.C., Diene, C., Drummond, J., Do, S., Fan, E., Harstad, E.B., Hodges, A., Hu, H., Jia, W., Kofie, W., Kolesnikov, A., Lyssikatos, J.P., Ly, J., Matteucci, M., Moffat, J.G., Munugalavadla, V., Murray, J., Nash, D., Noland, C.L., Del Rosario, G., Ross, L., Rouse, C., Sharpe, A., Slaga, D., Sun, M., Tsui, V., Wallweber, H., Yu, S.F., Ebens, A.J.
J. Med. Chem.
HeaderTransferase
Released2019-01-15
Resolution1.710
CATH Insert Date03 Mar, 2019

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Mar, 2019 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6no9A01 04 Mar, 2019 3.30.200.20 Assigned
6no9A02 04 Mar, 2019 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P11309 PIM1_HUMAN Homo sapiens Serine/threonine-protein kinase pim-1