PDB 6nlh

PDB Links
Overview

PDB Information

PDB	6NLH
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21(DE3)
Gene Source	Homo sapiens
Primary Citation	Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo. Roland, B.P., Richards, K.R., Hrizo, S.L., Eicher, S., Barile, Z.J., Chang, T.C., Savon, G., Bianchi, P., Fermo, E., Ricerca, B.M., Tortorolo, L., Vockley, J., VanDemark, A.P., Palladino, M.J. Biochim Biophys Acta Mol Basis Dis
Header	Isomerase
Released	2019-01-08
Resolution	2.200
CATH Insert Date	23 Jun, 2019

PDB Images (9)

Image of CATH 6nlh

6nlh

PDB 6nlh

Image of CATH 6nlhA

6nlhA

PDB Chain 6nlhA

Image of CATH 6nlhB

6nlhB

PDB Chain 6nlhB

Image of CATH 6nlhC

6nlhC

PDB Chain 6nlhC

Image of CATH 6nlhD

6nlhD

PDB Chain 6nlhD

Image of CATH 6nlhE

6nlhE

PDB Chain 6nlhE

Image of CATH 6nlhF

6nlhF

PDB Chain 6nlhF

Image of CATH 6nlhG

6nlhG

PDB Chain 6nlhG

Image of CATH 6nlhH

6nlhH

PDB Chain 6nlhH

PDB Prints

PDB Chains (8)

Chain ID	Date inserted into CATH	CATH Status
A	23 Jun, 2019	New
B	23 Jun, 2019	New
C	23 Jun, 2019	New
D	23 Jun, 2019	New
E	23 Jun, 2019	New
F	23 Jun, 2019	New
G	23 Jun, 2019	New
H	23 Jun, 2019	New

CATH Domains (0)

Domain ID	Date inserted into CATH	Superfamily	CATH Status

UniProtKB Entries (8)

Accession	Gene ID	Taxon	Description
P60174	TPIS_HUMAN	Homo sapiens	Triosephosphate isomerase
P60174	TPIS_HUMAN	Homo sapiens	Triosephosphate isomerase
P60174	TPIS_HUMAN	Homo sapiens	Triosephosphate isomerase
P60174	TPIS_HUMAN	Homo sapiens	Triosephosphate isomerase
P60174	TPIS_HUMAN	Homo sapiens	Triosephosphate isomerase
P60174	TPIS_HUMAN	Homo sapiens	Triosephosphate isomerase
P60174	TPIS_HUMAN	Homo sapiens	Triosephosphate isomerase
P60174	TPIS_HUMAN	Homo sapiens	Triosephosphate isomerase