PDB 6nji

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Overview

PDB Information

PDB	6NJI
Method	X-RAY DIFFRACTION
Host Organism	Trichoplusia ni
Gene Source	Homo sapiens
Primary Citation	Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders. Gurney, M.E., Nugent, R.A., Mo, X., Sindac, J.A., Hagen, T.J., Fox III, D., O'Donnell, J.M., Zhang, C., Xu, Y., Zhang, H.T., Groppi, V.E., Bailie, M., White, R.E., Romero, D.L., Vellekoop, A.S., Walker, J.R., Surman, M.D., Zhu, L., Campbell, R.F. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2019-01-03
Resolution	2.450
CATH Insert Date	12 May, 2019

PDB Images (5)

Image of CATH 6nji

6nji

PDB 6nji

Image of CATH 6njiA

6njiA

PDB Chain 6njiA

Image of CATH 6njiB

6njiB

PDB Chain 6njiB

Image of CATH 6njiA00

6njiA00

CATH Domain 6njiA00

Image of CATH 6njiB00

6njiB00

CATH Domain 6njiB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	12 May, 2019	Chopped
B	12 May, 2019	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6njiA00	13 May, 2019	1.10.1300.10	Assigned
6njiB00	13 May, 2019	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D