PDB 6nhb

PDB Information

PDB6NHB
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold.
Do, H.T., Li, H., Chreifi, G., Poulos, T.L., Silverman, R.B.
J. Med. Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2018-12-21
Resolution2.030
CATH Insert Date17 Mar, 2019

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 17 Mar, 2019 Chopped
B 17 Mar, 2019 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
6nhbA01 18 Mar, 2019 3.90.340.10 Assigned
6nhbA02 18 Mar, 2019 3.90.440.10 Assigned
6nhbA03 18 Mar, 2019 3.90.1230.10 Assigned
6nhbB01 18 Mar, 2019 3.90.340.10 Assigned
6nhbB02 18 Mar, 2019 3.90.440.10 Assigned
6nhbB03 18 Mar, 2019 3.90.1230.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P29475 NOS1_HUMAN Homo sapiens Nitric oxide synthase, brain
P29475 NOS1_HUMAN Homo sapiens Nitric oxide synthase, brain