PDB 6nh6

PDB Information

PDB6NH6
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold.
Do, H.T., Li, H., Chreifi, G., Poulos, T.L., Silverman, R.B.
J. Med. Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2018-12-21
Resolution2.190
CATH Insert Date17 Mar, 2019

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 17 Mar, 2019 Chopped
B 17 Mar, 2019 Chopped
C 17 Mar, 2019 Chopped
D 17 Mar, 2019 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
6nh6A01 18 Mar, 2019 3.90.340.10 Assigned
6nh6A02 18 Mar, 2019 3.90.440.10 Assigned
6nh6A03 18 Mar, 2019 3.90.1230.10 Assigned
6nh6B01 18 Mar, 2019 3.90.340.10 Assigned
6nh6B02 18 Mar, 2019 3.90.440.10 Assigned
6nh6B03 18 Mar, 2019 3.90.1230.10 Assigned
6nh6C01 18 Mar, 2019 3.90.340.10 Assigned
6nh6C02 18 Mar, 2019 3.90.440.10 Assigned
6nh6C03 18 Mar, 2019 3.90.1230.10 Assigned
6nh6D01 18 Mar, 2019 3.90.340.10 Assigned
6nh6D02 18 Mar, 2019 3.90.440.10 Assigned
6nh6D03 18 Mar, 2019 3.90.1230.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial