PDB 6n6o

PDB Information

PDB6N6O
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design and Optimization Leading to an Orally Active TTK Protein Kinase Inhibitor with Robust Single Agent Efficacy.
Riggs, J.R., Elsner, J., Cashion, D., Robinson, D., Tehrani, L., Nagy, M., Fultz, K.E., Krishna Narla, R., Peng, X., Tran, T., Kulkarni, A., Bahmanyar, S., Condroski, K., Pagarigan, B., Fenalti, G., LeBrun, L., Leftheris, K., Zhu, D., Boylan, J.F.
J.Med.Chem.
HeaderSignaling Protein
Released2018-11-26
Resolution2.600
CATH Insert Date19 May, 2019

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 19 May, 2019 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6n6oA01 20 May, 2019 3.30.200.20 Assigned
6n6oA02 20 May, 2019 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P33981 TTK_HUMAN Homo sapiens Dual specificity protein kinase TTK