PDB 6mdc

PDB Information

PDB6MDC
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors.
Bagdanoff, J.T., Chen, Z., Acker, M., Chen, Y.N., Chan, H., Dore, M., Firestone, B., Fodor, M., Fortanet, J., Hentemann, M., Kato, M., Koenig, R., LaBonte, L.R., Liu, S., Mohseni, M., Ntaganda, R., Sarver, P., Smith, T., Sendzik, M., Stams, T., Spence, S., Towler, C., Wang, H., Wang, P., Williams, S.L., LaMarche, M.J.
J. Med. Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2018-09-04
Resolution2.140
CATH Insert Date17 Feb, 2019

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 17 Feb, 2019 Chopped
B 17 Feb, 2019 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
6mdcA01 18 Feb, 2019 3.30.505.10 Assigned
6mdcA02 18 Feb, 2019 3.30.505.10 Assigned
6mdcA03 18 Feb, 2019 3.90.190.10 Assigned
6mdcB01 18 Feb, 2019 3.30.505.10 Assigned
6mdcB02 18 Feb, 2019 3.30.505.10 Assigned
6mdcB03 18 Feb, 2019 3.90.190.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q06124 PTN11_HUMAN Homo sapiens Tyrosine-protein phosphatase non-receptor type 11
Q06124 PTN11_HUMAN Homo sapiens Tyrosine-protein phosphatase non-receptor type 11