PDB 6mda

PDB Links
Overview

PDB Information

PDB	6MDA
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors. Bagdanoff, J.T., Chen, Z., Acker, M., Chen, Y.N., Chan, H., Dore, M., Firestone, B., Fodor, M., Fortanet, J., Hentemann, M., Kato, M., Koenig, R., LaBonte, L.R., Liu, S., Mohseni, M., Ntaganda, R., Sarver, P., Smith, T., Sendzik, M., Stams, T., Spence, S., Towler, C., Wang, H., Wang, P., Williams, S.L., LaMarche, M.J. J. Med. Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2018-09-04
Resolution	2.210
CATH Insert Date	17 Feb, 2019

PDB Images (9)

Image of CATH 6mda

6mda

PDB 6mda

Image of CATH 6mdaA

6mdaA

PDB Chain 6mdaA

Image of CATH 6mdaB

6mdaB

PDB Chain 6mdaB

Image of CATH 6mdaA01

6mdaA01

CATH Domain 6mdaA01

Image of CATH 6mdaA02

6mdaA02

CATH Domain 6mdaA02

Image of CATH 6mdaA03

6mdaA03

CATH Domain 6mdaA03

Image of CATH 6mdaB01

6mdaB01

CATH Domain 6mdaB01

Image of CATH 6mdaB02

6mdaB02

CATH Domain 6mdaB02

Image of CATH 6mdaB03

6mdaB03

CATH Domain 6mdaB03

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	17 Feb, 2019	Chopped
B	17 Feb, 2019	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6mdaA01	18 Feb, 2019	3.30.505.10	Assigned
6mdaA02	18 Feb, 2019	3.30.505.10	Assigned
6mdaA03	18 Feb, 2019	3.90.190.10	Assigned
6mdaB01	18 Feb, 2019	3.30.505.10	Assigned
6mdaB02	18 Feb, 2019	3.30.505.10	Assigned
6mdaB03	18 Feb, 2019	3.90.190.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q06124	PTN11_HUMAN	Homo sapiens	Tyrosine-protein phosphatase non-receptor type 11
Q06124	PTN11_HUMAN	Homo sapiens	Tyrosine-protein phosphatase non-receptor type 11