PDB 6md9

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Overview

PDB Information

PDB	6MD9
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors. Bagdanoff, J.T., Chen, Z., Acker, M., Chen, Y.N., Chan, H., Dore, M., Firestone, B., Fodor, M., Fortanet, J., Hentemann, M., Kato, M., Koenig, R., LaBonte, L.R., Liu, S., Mohseni, M., Ntaganda, R., Sarver, P., Smith, T., Sendzik, M., Stams, T., Spence, S., Towler, C., Wang, H., Wang, P., Williams, S.L., LaMarche, M.J. J. Med. Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2018-09-04
Resolution	2.120
CATH Insert Date	17 Feb, 2019

PDB Images (9)

Image of CATH 6md9

6md9

PDB 6md9

Image of CATH 6md9A

6md9A

PDB Chain 6md9A

Image of CATH 6md9B

6md9B

PDB Chain 6md9B

Image of CATH 6md9A01

6md9A01

CATH Domain 6md9A01

Image of CATH 6md9A02

6md9A02

CATH Domain 6md9A02

Image of CATH 6md9A03

6md9A03

CATH Domain 6md9A03

Image of CATH 6md9B01

6md9B01

CATH Domain 6md9B01

Image of CATH 6md9B02

6md9B02

CATH Domain 6md9B02

Image of CATH 6md9B03

6md9B03

CATH Domain 6md9B03

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	17 Feb, 2019	Chopped
B	17 Feb, 2019	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6md9A01	18 Feb, 2019	3.30.505.10	Assigned
6md9A02	18 Feb, 2019	3.30.505.10	Assigned
6md9A03	18 Feb, 2019	3.90.190.10	Assigned
6md9B01	18 Feb, 2019	3.30.505.10	Assigned
6md9B02	18 Feb, 2019	3.30.505.10	Assigned
6md9B03	18 Feb, 2019	3.90.190.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q06124	PTN11_HUMAN	Homo sapiens	Tyrosine-protein phosphatase non-receptor type 11
Q06124	PTN11_HUMAN	Homo sapiens	Tyrosine-protein phosphatase non-receptor type 11