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PDB Information

PDB6MCS
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
Halogen Bond Interactions of Novel HIV-1 Protease Inhibitors (PI) (GRL-001-15 and GRL-003-15) with the Flap of Protease Are Critical for Their Potent Activity against Wild-Type HIV-1 and Multi-PI-Resistant Variants.
Hattori, S.I., Hayashi, H., Bulut, H., Rao, K.V., Nyalapatla, P.R., Hasegawa, K., Aoki, M., Ghosh, A.K., Mitsuya, H.
Antimicrob.Agents Chemother.
HeaderViral Protein
Released2018-09-02
Resolution1.520
CATH Insert Date28 Apr, 2019

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 Apr, 2019 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
6mcsA00 29 Apr, 2019 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P12497 POL_HV1N5 Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) Gag-Pol polyprotein
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