PDB Information

PDB6J1L
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceHomo sapiens
Primary Citation
Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable ROR gamma Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer.
Zhang, Y., Wu, X., Xue, X., Li, C., Wang, J., Wang, R., Zhang, C., Wang, C., Shi, Y., Zou, L., Li, Q., Huang, Z., Hao, X., Loomes, K., Wu, D., Chen, H.W., Xu, J., Xu, Y.
J.Med.Chem.
HeaderDna Binding Protein
Released2018-12-28
Resolution2.300
CATH Insert Date05 May, 2019

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 05 May, 2019 Chopped
B 05 May, 2019 Chopped
C 05 May, 2019 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
6j1lA00 06 May, 2019 1.10.565.10 Assigned
6j1lB00 06 May, 2019 1.10.565.10 Assigned
6j1lC00 06 May, 2019 1.10.565.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma