PDB 6ijh

PDB Information

PDB6IJH
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceHomo sapiens
Primary Citation
Validation of Phosphodiesterase-10 as a Novel Target for Pulmonary Arterial Hypertension via Highly Selective and Subnanomolar Inhibitors.
Huang, Y.Y., Yu, Y.F., Zhang, C., Chen, Y., Zhou, Q., Li, Z., Zhou, S., Li, Z., Guo, L., Wu, D., Wu, Y., Luo, H.B.
J. Med. Chem.
HeaderHydrolase/Inhibitor
Released2018-10-10
Resolution2.600
CATH Insert Date14 Apr, 2019

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 14 Apr, 2019 Chopped
B 14 Apr, 2019 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6ijhA00 15 Apr, 2019 1.10.1300.10 Assigned
6ijhB00 15 Apr, 2019 1.10.1300.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9Y233 PDE10_HUMAN Homo sapiens cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233 PDE10_HUMAN Homo sapiens cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A