Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel.
Haile, P.A., Casillas, L.N., Bury, M.J., Mehlmann, J.F., Singhaus Jr., R., Charnley, A.K., Hughes, T.V., DeMartino, M.P., Wang, G.Z., Romano, J.J., Dong, X., Plotnikov, N.V., Lakdawala, A.S., Convery, M.A., Votta, B.J., Lipshutz, D.B., Desai, B.M., Swift, B., Capriotti, C.A., Berger, S.B., Mahajan, M.K., Reilly, M.A., Rivera, E.J., Sun, H.H., Nagilla, R., LePage, C., Ouellette, M.T., Totoritis, R.D., Donovan, B.T., Brown, B.S., Chaudhary, K.W., Gough, P.J., Bertin, J., Marquis, R.W.
ACS Med Chem Lett