PDB 6hd6

PDB Links
Overview

PDB Information

PDB	6HD6
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Mus musculus
Primary Citation	Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1. Schoepfer, J., Jahnke, W., Berellini, G., Buonamici, S., Cotesta, S., Cowan-Jacob, S.W., Dodd, S., Drueckes, P., Fabbro, D., Gabriel, T., Groell, J.M., Grotzfeld, R.M., Hassan, A.Q., Henry, C., Iyer, V., Jones, D., Lombardo, F., Loo, A., Manley, P.W., Pelle, X., Rummel, G., Salem, B., Warmuth, M., Wylie, A.A., Zoller, T., Marzinzik, A.L., Furet, P. J. Med. Chem.
Header	Transferase
Released	2018-08-17
Resolution	2.300
CATH Insert Date	16 Sep, 2018

PDB Images (7)

Image of CATH 6hd6

6hd6

PDB 6hd6

Image of CATH 6hd6A

6hd6A

PDB Chain 6hd6A

Image of CATH 6hd6B

6hd6B

PDB Chain 6hd6B

Image of CATH 6hd6A01

6hd6A01

CATH Domain 6hd6A01

Image of CATH 6hd6A02

6hd6A02

CATH Domain 6hd6A02

Image of CATH 6hd6B01

6hd6B01

CATH Domain 6hd6B01

Image of CATH 6hd6B02

6hd6B02

CATH Domain 6hd6B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	16 Sep, 2018	Chopped
B	16 Sep, 2018	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6hd6A01	17 Sep, 2018	3.30.200.20	Assigned
6hd6A02	17 Sep, 2018	1.10.510.10	Assigned
6hd6B01	17 Sep, 2018	3.30.200.20	Assigned
6hd6B02	17 Sep, 2018	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P00520	ABL1_MOUSE	Mus musculus	Tyrosine-protein kinase ABL1
P00520	ABL1_MOUSE	Mus musculus	Tyrosine-protein kinase ABL1