PDB 6hd4

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PDB Links
Overview

PDB Information

PDB	6HD4
Method	X-RAY DIFFRACTION
Host Organism	Baculovirus expression vector pFastBac1-HM
Gene Source	Mus musculus
Primary Citation	Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1. Schoepfer, J., Jahnke, W., Berellini, G., Buonamici, S., Cotesta, S., Cowan-Jacob, S.W., Dodd, S., Drueckes, P., Fabbro, D., Gabriel, T., Groell, J.M., Grotzfeld, R.M., Hassan, A.Q., Henry, C., Iyer, V., Jones, D., Lombardo, F., Loo, A., Manley, P.W., Pelle, X., Rummel, G., Salem, B., Warmuth, M., Wylie, A.A., Zoller, T., Marzinzik, A.L., Furet, P. J. Med. Chem.
Header	Transferase
Released	2018-08-17
Resolution	2.030
CATH Insert Date	16 Dec, 2018

PDB Images (7)

Image of CATH 6hd4

6hd4

PDB 6hd4

Image of CATH 6hd4A

6hd4A

PDB Chain 6hd4A

Image of CATH 6hd4B

6hd4B

PDB Chain 6hd4B

Image of CATH 6hd4A01

6hd4A01

CATH Domain 6hd4A01

Image of CATH 6hd4A02

6hd4A02

CATH Domain 6hd4A02

Image of CATH 6hd4B01

6hd4B01

CATH Domain 6hd4B01

Image of CATH 6hd4B02

6hd4B02

CATH Domain 6hd4B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	16 Dec, 2018	Chopped
B	16 Dec, 2018	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6hd4A01	28 Feb, 2019	3.30.200.20	Assigned
6hd4A02	28 Feb, 2019	1.10.510.10	Assigned
6hd4B01	28 Feb, 2019	3.30.200.20	Assigned
6hd4B02	28 Feb, 2019	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P00520	ABL1_MOUSE	Mus musculus	Tyrosine-protein kinase ABL1
P00520	ABL1_MOUSE	Mus musculus	Tyrosine-protein kinase ABL1