PDB 6gmx
PDB Information
| PDB | 6GMX |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Surface Probing by Fragment-Based Screening and Computational Methods Identifies Ligandable Pockets on the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase.
J. Med. Chem.
|
| Header | Oncoprotein |
| Released | 2018-05-28 |
| Resolution | 2.530 |
| CATH Insert Date | 12 Aug, 2018 |
PDB Images (29)
6gmx
PDB 6gmx
6gmxA
PDB Chain 6gmxA
6gmxB
PDB Chain 6gmxB
6gmxC
PDB Chain 6gmxC
6gmxD
PDB Chain 6gmxD
6gmxE
PDB Chain 6gmxE
6gmxF
PDB Chain 6gmxF
6gmxG
PDB Chain 6gmxG
6gmxH
PDB Chain 6gmxH
6gmxI
PDB Chain 6gmxI
6gmxJ
PDB Chain 6gmxJ
6gmxK
PDB Chain 6gmxK
6gmxL
PDB Chain 6gmxL
6gmxA00
CATH Domain 6gmxA00
6gmxB00
CATH Domain 6gmxB00
6gmxC01
CATH Domain 6gmxC01
6gmxC02
CATH Domain 6gmxC02
6gmxD00
CATH Domain 6gmxD00
6gmxE00
CATH Domain 6gmxE00
6gmxF01
CATH Domain 6gmxF01
6gmxF02
CATH Domain 6gmxF02
6gmxG00
CATH Domain 6gmxG00
6gmxH00
CATH Domain 6gmxH00
6gmxI01
CATH Domain 6gmxI01
6gmxI02
CATH Domain 6gmxI02
6gmxJ00
CATH Domain 6gmxJ00
6gmxK00
CATH Domain 6gmxK00
6gmxL01
CATH Domain 6gmxL01
6gmxL02
CATH Domain 6gmxL02
PDB Prints
PDB Chains (12)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 12 Aug, 2018 | Chopped |
| B | 12 Aug, 2018 | Chopped |
| C | 12 Aug, 2018 | Chopped |
| D | 12 Aug, 2018 | Chopped |
| E | 12 Aug, 2018 | Chopped |
| F | 12 Aug, 2018 | Chopped |
| G | 12 Aug, 2018 | Chopped |
| H | 12 Aug, 2018 | Chopped |
| I | 12 Aug, 2018 | Chopped |
| J | 12 Aug, 2018 | Chopped |
| K | 12 Aug, 2018 | Chopped |
| L | 12 Aug, 2018 | Chopped |
CATH Domains (16)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 6gmxA00 | 13 Aug, 2018 | 3.10.20.90 | Assigned |
| 6gmxB00 | 13 Aug, 2018 | 3.30.710.10 | Assigned |
| 6gmxC01 | 13 Aug, 2018 | 2.60.40.780 | Assigned |
| 6gmxC02 | 13 Aug, 2018 | 1.10.750.10 | Assigned |
| 6gmxD00 | 13 Aug, 2018 | 3.10.20.90 | Assigned |
| 6gmxE00 | 13 Aug, 2018 | 3.30.710.10 | Assigned |
| 6gmxF01 | 13 Aug, 2018 | 2.60.40.780 | Assigned |
| 6gmxF02 | 13 Aug, 2018 | 1.10.750.10 | Assigned |
| 6gmxG00 | 13 Aug, 2018 | 3.10.20.90 | Assigned |
| 6gmxH00 | 13 Aug, 2018 | 3.30.710.10 | Assigned |
| 6gmxI01 | 13 Aug, 2018 | 2.60.40.780 | Assigned |
| 6gmxI02 | 13 Aug, 2018 | 1.10.750.10 | Assigned |
| 6gmxJ00 | 13 Aug, 2018 | 3.10.20.90 | Assigned |
| 6gmxK00 | 13 Aug, 2018 | 3.30.710.10 | Assigned |
| 6gmxL01 | 13 Aug, 2018 | 2.60.40.780 | Assigned |
| 6gmxL02 | 13 Aug, 2018 | 1.10.750.10 | Assigned |
UniProtKB Entries (12)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
