PDB Information

PDB6GL3
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of a Potent, Orally Bioavailable PI4KIII beta Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment in Vivo.
Reuberson, J., Horsley, H., Franklin, R.J., Ford, D., Neuss, J., Brookings, D., Huang, Q., Vanderhoydonck, B., Gao, L.J., Jang, M.Y., Herdewijn, P., Ghawalkar, A., Fallah-Arani, F., Khan, A.R., Henshall, J., Jairaj, M., Malcolm, S., Ward, E., Shuttleworth, L., Lin, Y., Li, S., Louat, T., Waer, M., Herman, J., Payne, A., Ceska, T., Doyle, C., Pitt, W., Calmiano, M., Augustin, M., Steinbacher, S., Lammens, A., Allen, R.
J. Med. Chem.
HeaderImmune System
Released2018-05-22
Resolution2.770
CATH Insert Date19 Aug, 2018

PDB Images (3)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 19 Aug, 2018 Holding pen
B 19 Aug, 2018 Holding pen

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9UBF8 PI4KB_HUMAN Homo sapiens Phosphatidylinositol 4-kinase beta
Q9UBF8 PI4KB_HUMAN Homo sapiens Phosphatidylinositol 4-kinase beta