Fragment-Based Discovery of a Potent, Orally Bioavailable Inhibitor That Modulates the Phosphorylation and Catalytic Activity of ERK1/2.
Heightman, T.D., Berdini, V., Braithwaite, H., Buck, I.M., Cassidy, M., Castro, J., Courtin, A., Day, J.E.H., East, C., Fazal, L., Graham, B., Griffiths-Jones, C.M., Lyons, J.F., Martins, V., Muench, S., Munck, J.M., Norton, D., O'Reilly, M., Palmer, N., Pathuri, P., Reader, M., Rees, D.C., Rich, S.J., Richardson, C., Saini, H., Thompson, N.T., Wallis, N.G., Walton, H., Wilsher, N.E., Woolford, A.J., Cooke, M., Cousin, D., Onions, S., Shannon, J., Watts, J., Murray, C.W.
J. Med. Chem.