PDB 6g07

PDB Information

PDB6G07
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceHomo sapiens
Primary Citation
Optimizing a Weakly Binding Fragment into a Potent ROR gamma t Inverse Agonist with Efficacy in an in Vivo Inflammation Model.
Carcache, D.A., Vulpetti, A., Kallen, J., Mattes, H., Orain, D., Stringer, R., Vangrevelinghe, E., Wolf, R.M., Kaupmann, K., Ottl, J., Dawson, J., Cooke, N.G., Hoegenauer, K., Billich, A., Wagner, J., Guntermann, C., Hintermann, S.
J. Med. Chem.
HeaderTranscription
Released2018-03-16
Resolution1.660
CATH Insert Date22 Jul, 2018

PDB Images (13)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 22 Jul, 2018 Chopped
B 22 Jul, 2018 Chopped
C 22 Jul, 2018 Chopped
D 22 Jul, 2018 Chopped
P 22 Jul, 2018 Rejected
Q 22 Jul, 2018 Rejected
R 22 Jul, 2018 Rejected
S 22 Jul, 2018 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6g07A00 23 Jul, 2018 1.10.565.10 Assigned
6g07B00 23 Jul, 2018 1.10.565.10 Assigned
6g07C00 23 Jul, 2018 1.10.565.10 Assigned
6g07D00 23 Jul, 2018 1.10.565.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma
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