PDB 6fek

PDB Information

PDB6FEK
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
A secondary RET mutation in the activation loop conferring resistance to vandetanib.
Nakaoku, T., Kohno, T., Araki, M., Niho, S., Chauhan, R., Knowles, P.P., Tsuchihara, K., Matsumoto, S., Shimada, Y., Mimaki, S., Ishii, G., Ichikawa, H., Nagatoishi, S., Tsumoto, K., Okuno, Y., Yoh, K., McDonald, N.Q., Goto, K.
Nat Commun
HeaderOncoprotein
Released2018-01-02
Resolution2.300
CATH Insert Date03 Jun, 2018

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6fekA01 29 Jun, 2018 3.30.200.20 Assigned
6fekA02 29 Jun, 2018 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P07949 RET_HUMAN Homo sapiens Proto-oncogene tyrosine-protein kinase receptor Ret