PDB 6ex8

PDB Information

PDB6EX8
MethodX-RAY DIFFRACTION
Host OrganismKomagataella pastoris
Gene SourceTrypanosoma brucei rhodesiense
Primary Citation
Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors.
Giroud, M., Dietzel, U., Anselm, L., Banner, D., Kuglstatter, A., Benz, J., Blanc, J.B., Gaufreteau, D., Liu, H., Lin, X., Stich, A., Kuhn, B., Schuler, F., Kaiser, M., Brun, R., Schirmeister, T., Kisker, C., Diederich, F., Haap, W.
J. Med. Chem.
HeaderHydrolase
Released2017-11-07
Resolution1.600
CATH Insert Date03 Jun, 2018

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6ex8A00 29 Jun, 2018 3.90.70.10 Assigned
6ex8B00 29 Jun, 2018 3.90.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q95PM0 Q95PM0_TRYBR Trypanosoma brucei rhodesiense Cysteine protease
Q95PM0 Q95PM0_TRYBR Trypanosoma brucei rhodesiense Cysteine protease