PDB 6edl

PDB Information

PDB6EDL
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
Discovery of Potent, Selective, and Brain-Penetrant 1 H-Pyrazol-5-yl-1 H-pyrrolo[2,3- b]pyridines as Anaplastic Lymphoma Kinase (ALK) Inhibitors.
Fushimi, M., Fujimori, I., Wakabayashi, T., Hasui, T., Kawakita, Y., Imamura, K., Kato, T., Murakami, M., Ishii, T., Kikko, Y., Kasahara, M., Nakatani, A., Hiura, Y., Miyamoto, M., Saikatendu, K., Zou, H., Lane, S.W., Lawson, J.D., Imoto, H.
J.Med.Chem.
HeaderTransferase/Inhibitor
Released2018-08-09
Resolution2.800
CATH Insert Date05 May, 2019

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 May, 2019 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6edlA01 06 May, 2019 3.30.200.20 Assigned
6edlA02 06 May, 2019 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9UM73 ALK_HUMAN Homo sapiens ALK tyrosine kinase receptor