PDB 6e4w

PDB Links
Overview

PDB Information

PDB	6E4W
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Rattus norvegicus
Primary Citation	Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK). Ryder, T.F., Calabrese, M.F., Walker, G.S., Cameron, K.O., Reyes, A.R., Borzilleri, K.A., Delmore, J., Miller, R., Kurumbail, R.G., Ward, J., Kung, D.W., Brown, J.A., Edmonds, D.J., Eng, H., Wolford, A.C., Kalgutkar, A.S. J. Med. Chem.
Header	Transferase
Released	2018-07-18
Resolution	3.350
CATH Insert Date	12 Aug, 2018

PDB Images (5)

Image of CATH 6e4w

6e4w

PDB 6e4w

Image of CATH 6e4wA

6e4wA

PDB Chain 6e4wA

Image of CATH 6e4wB

6e4wB

PDB Chain 6e4wB

Image of CATH 6e4wC

6e4wC

PDB Chain 6e4wC

Image of CATH 6e4wC00

6e4wC00

CATH Domain 6e4wC00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	12 Aug, 2018	Holding pen
B	12 Aug, 2018	Holding pen
C	12 Aug, 2018	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6e4wC00	13 Aug, 2018		Holding pen

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P80386	AAKB1_RAT	Rattus norvegicus	5'-AMP-activated protein kinase subunit beta-1
P54645	AAPK1_RAT	Rattus norvegicus	5'-AMP-activated protein kinase catalytic subunit alpha-1
P80385	AAKG1_RAT	Rattus norvegicus	5'-AMP-activated protein kinase subunit gamma-1