PDB 6dkw

PDB Information

PDB6DKW
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain.
Bagal, S.K., Andrews, M., Bechle, B.M., Bian, J., Bilsland, J., Blakemore, D.C., Braganza, J.F., Bungay, P.J., Corbett, M.S., Cronin, C.N., Cui, J.J., Dias, R., Flanagan, N.J., Greasley, S.E., Grimley, R., James, K., Johnson, E., Kitching, L., Kraus, M.L., McAlpine, I., Nagata, A., Ninkovic, S., Omoto, K., Scales, S., Skerratt, S.E., Sun, J., Tran-Dube, M., Waldron, G.J., Wang, F., Warmus, J.S.
J. Med. Chem.
HeaderTransferase/Transferase Inhibitor
Released2018-05-31
Resolution2.910
CATH Insert Date16 Jul, 2018

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Jul, 2018 Chopped
B 16 Jul, 2018 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6dkwA01 19 Jul, 2018 3.30.200.20 Assigned
6dkwA02 19 Jul, 2018 1.10.510.10 Assigned
6dkwB01 19 Jul, 2018 3.30.200.20 Assigned
6dkwB02 19 Jul, 2018 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P04629 NTRK1_HUMAN Homo sapiens High affinity nerve growth factor receptor
P04629 NTRK1_HUMAN Homo sapiens High affinity nerve growth factor receptor