PDB 6dkj

PDB Information

PDB6DKJ
MethodX-RAY DIFFRACTION
Host OrganismCricetulus griseus
Gene SourceHomo sapiens
Primary Citation
Anti-obesity effects of GIPR antagonists alone and in combination with GLP-1R agonists in preclinical models.
Killion, E.A., Wang, J., Yie, J., Shi, S.D., Bates, D., Min, X., Komorowski, R., Hager, T., Deng, L., Atangan, L., Lu, S.C., Kurzeja, R.J.M., Sivits, G., Lin, J., Chen, Q., Wang, Z., Thibault, S.A., Abbott, C.M., Meng, T., Clavette, B., Murawsky, C.M., Foltz, I.N., Rottman, J.B., Hale, C., Veniant, M.M., Lloyd, D.J.
Sci Transl Med
HeaderSignaling Protein
Released2018-05-29
Resolution1.950
CATH Insert Date12 May, 2019

PDB Images (11)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 12 May, 2019 Holding pen
B 12 May, 2019 Chopped
C 12 May, 2019 Holding pen
D 12 May, 2019 Holding pen
H 12 May, 2019 Holding pen
L 12 May, 2019 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6dkjB01 13 May, 2019 2.60.40.10 Assigned
6dkjB02 13 May, 2019 2.60.40.10 Assigned
6dkjL01 13 May, 2019 2.60.40.10 Assigned
6dkjL02 13 May, 2019 2.60.40.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P0DOX5 IGG1_HUMAN Homo sapiens Immunoglobulin gamma-1 heavy chain
P48546 GIPR_HUMAN Homo sapiens Gastric inhibitory polypeptide receptor
P0DOX5 IGG1_HUMAN Homo sapiens Immunoglobulin gamma-1 heavy chain
P48546 GIPR_HUMAN Homo sapiens Gastric inhibitory polypeptide receptor