PDB Information

PDB6DJC
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth.
Ren, C., Zhang, G., Han, F., Fu, S., Cao, Y., Zhang, F., Zhang, Q., Meslamani, J., Xu, Y., Ji, D., Cao, L., Zhou, Q., Cheung, K.L., Sharma, R., Babault, N., Yi, Z., Zhang, W., Walsh, M.J., Zeng, L., Zhou, M.M.
Proc. Natl. Acad. Sci. U.S.A.
HeaderTranscription/Inhibitor
Released2018-05-25
Resolution1.460
CATH Insert Date29 Jul, 2018

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jul, 2018 Chopped
B 29 Jul, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6djcA01 30 Jul, 2018 1.20.920.10 Assigned
6djcB01 30 Jul, 2018 1.20.920.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4