PDB 6di0

PDB Information

PDB6DI0
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of a novel series of pyridine and pyrimidine carboxamides as potent and selective covalent inhibitors of Btk.
Caldwell, R., Liu-Bujalski, L., Qiu, H., Mochalkin, I., Jones, R., Neagu, C., Goutopoulos, A., Grenningloh, R., Johnson, T., Sherer, B., Gardberg, A., Follis, A.V., Morandi, F., Head, J.
Bioorg. Med. Chem. Lett.
HeaderTransferase/Transferase Inhibitor
Released2018-05-22
Resolution1.300
CATH Insert Date16 Dec, 2018

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6di0A01 28 Feb, 2019 3.30.200.20 Assigned
6di0A02 28 Feb, 2019 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q06187 BTK_HUMAN Homo sapiens Tyrosine-protein kinase BTK