PDB 6dhc

PDB Links
Overview

PDB Information

PDB	6DHC
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Design, synthesis, X-ray studies, and biological evaluation of novel BACE1 inhibitors with bicyclic isoxazoline carboxamides as the P3 ligand. Ghosh, A.K., Ghosh, K., Brindisi, M., Lendy, E.K., Yen, Y.C., Kumaragurubaran, N., Huang, X., Tang, J., Mesecar, A.D. Bioorg. Med. Chem. Lett.
Header	Hydrolase
Released	2018-05-19
Resolution	2.850
CATH Insert Date	29 Jul, 2018

PDB Images (10)

Image of CATH 6dhc

6dhc

PDB 6dhc

Image of CATH 6dhcA

6dhcA

PDB Chain 6dhcA

Image of CATH 6dhcB

6dhcB

PDB Chain 6dhcB

Image of CATH 6dhcC

6dhcC

PDB Chain 6dhcC

Image of CATH 6dhcA01

6dhcA01

CATH Domain 6dhcA01

Image of CATH 6dhcA02

6dhcA02

CATH Domain 6dhcA02

Image of CATH 6dhcB01

6dhcB01

CATH Domain 6dhcB01

Image of CATH 6dhcB02

6dhcB02

CATH Domain 6dhcB02

Image of CATH 6dhcC01

6dhcC01

CATH Domain 6dhcC01

Image of CATH 6dhcC02

6dhcC02

CATH Domain 6dhcC02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jul, 2018	Chopped
B	29 Jul, 2018	Chopped
C	29 Jul, 2018	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6dhcA01	30 Jul, 2018	2.40.70.10	Assigned
6dhcA02	30 Jul, 2018	2.40.70.10	Assigned
6dhcB01	30 Jul, 2018	2.40.70.10	Assigned
6dhcB02	30 Jul, 2018	2.40.70.10	Assigned
6dhcC01	30 Jul, 2018	2.40.70.10	Assigned
6dhcC02	30 Jul, 2018	2.40.70.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1