×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

PDB 6ct7

PDB Information

PDB6CT7
MethodX-RAY DIFFRACTION
Host OrganismCricetulus griseus
Gene SourceHomo sapiens
Primary Citation
Development of an aggregate-selective, human-derived alpha-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models.
Weihofen, A., Liu, Y., Arndt, J.W., Huy, C., Quan, C., Smith, B.A., Baeriswyl, J.L., Cavegn, N., Senn, L., Su, L., Marsh, G., Auluck, P.K., Montrasio, F., Nitsch, R.M., Hirst, W.D., Cedarbaum, J.M., Pepinsky, R.B., Grimm, J., Weinreb, P.H.
Neurobiol. Dis.
HeaderImmune System
Released2018-03-22
Resolution1.900
CATH Insert Date23 Dec, 2018

PDB Images (11)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 23 Dec, 2018 Holding pen
B 23 Dec, 2018 Chopped
H 23 Dec, 2018 Holding pen
L 23 Dec, 2018 Chopped
S 23 Dec, 2018 Rejected
T 23 Dec, 2018 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6ct7B01 27 Dec, 2018 2.60.40.10 Assigned
6ct7B02 27 Dec, 2018 2.60.40.10 Assigned
6ct7L01 27 Dec, 2018 2.60.40.10 Assigned
6ct7L02 27 Dec, 2018 2.60.40.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P37840 SYUA_HUMAN Homo sapiens Alpha-synuclein
P37840 SYUA_HUMAN Homo sapiens Alpha-synuclein
CATH-Gene3D is a Global Biodata Core Resource Learn more...