PDB 6cpw

PDB Information

PDB6CPW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceRattus norvegicus
Primary Citation
Discovery of 3(S)-thiomethyl pyrrolidine ERK inhibitors for oncology.
Boga, S.B., Alhassan, A.B., Cooper, A.B., Doll, R., Shih, N.Y., Shipps, G., Deng, Y., Zhu, H., Nan, Y., Sun, R., Zhu, L., Desai, J., Patel, M., Muppalla, K., Gao, X., Wang, J., Yao, X., Kelly, J., Gudipati, S., Paliwal, S., Tsui, H.C., Wang, T., Sherborne, B., Xiao, L., Hruza, A., Buevich, A., Zhang, L.K., Hesk, D., Samatar, A.A., Carr, D., Long, B., Black, S., Dayananth, P., Windsor, W., Kirschmeier, P., Bishop, R.
Bioorg. Med. Chem. Lett.
HeaderTransferase/Transferase Inhibitor
Released2018-03-14
Resolution1.850
CATH Insert Date03 Jun, 2018

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6cpwA01 29 Jun, 2018 3.30.200.20 Assigned
6cpwA02 29 Jun, 2018 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P63086 MK01_RAT Rattus norvegicus Mitogen-activated protein kinase 1