PDB Information

PDB6CG2
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli K-12
Gene SourceHomo sapiens
Primary Citation
Structure-based design and discovery of potent and selective KDM5 inhibitors.
Nie, Z., Shi, L., Lai, C., O'Connell, S.M., Xu, J., Stansfield, R.K., Hosfield, D.J., Veal, J.M., Stafford, J.A.
Bioorg. Med. Chem. Lett.
HeaderOxidoreductase/Inhibitor
Released2018-02-19
Resolution2.340
CATH Insert Date03 Jun, 2018

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped
C 03 Jun, 2018 Chopped
D 03 Jun, 2018 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6cg2A01 28 Jun, 2018 2.60.120.650 Assigned
6cg2B01 28 Jun, 2018 2.60.120.650 Assigned
6cg2C01 28 Jun, 2018 2.60.120.650 Assigned
6cg2D01 28 Jun, 2018 2.60.120.650 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
O75164 KDM4A_HUMAN Homo sapiens Lysine-specific demethylase 4A
O75164 KDM4A_HUMAN Homo sapiens Lysine-specific demethylase 4A
O75164 KDM4A_HUMAN Homo sapiens Lysine-specific demethylase 4A
O75164 KDM4A_HUMAN Homo sapiens Lysine-specific demethylase 4A