PDB 6c0s

PDB Information

PDB6C0S
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Pyridazine and pyridazinone derivatives as potent and selective factor XIa inhibitors.
Hu, Z., Wang, C., Han, W., Rossi, K.A., Bozarth, J.M., Wu, Y., Sheriff, S., Myers, J.E., Luettgen, J.M., Seiffert, D.A., Wexler, R.R., Quan, M.L.
Bioorg. Med. Chem. Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2018-01-02
Resolution2.350
CATH Insert Date03 Jun, 2018

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6c0sA01 28 Jun, 2018 Holding pen
6c0sA02 28 Jun, 2018 2.40.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P03951 FA11_HUMAN Homo sapiens Coagulation factor XI