PDB 6bw8

PDB Links
Overview

PDB Information

PDB	6BW8
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Optimization of Potent and Selective Tricyclic Indole Diazepinone Myeloid Cell Leukemia-1 Inhibitors Using Structure-Based Design. Shaw, S., Bian, Z., Zhao, B., Tarr, J.C., Veerasamy, N., Jeon, K.O., Belmar, J., Arnold, A.L., Fogarty, S.A., Perry, E., Sensintaffar, J.L., Camper, D.V., Rossanese, O.W., Lee, T., Olejniczak, E.T., Fesik, S.W. J. Med. Chem.
Header	Apoptosis
Released	2017-12-14
Resolution	2.900
CATH Insert Date	03 Jun, 2018

PDB Images (9)

Image of CATH 6bw8

6bw8

PDB 6bw8

Image of CATH 6bw8A

6bw8A

PDB Chain 6bw8A

Image of CATH 6bw8B

6bw8B

PDB Chain 6bw8B

Image of CATH 6bw8C

6bw8C

PDB Chain 6bw8C

Image of CATH 6bw8D

6bw8D

PDB Chain 6bw8D

Image of CATH 6bw8A01

6bw8A01

CATH Domain 6bw8A01

Image of CATH 6bw8B01

6bw8B01

CATH Domain 6bw8B01

Image of CATH 6bw8C01

6bw8C01

CATH Domain 6bw8C01

Image of CATH 6bw8D01

6bw8D01

CATH Domain 6bw8D01

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	03 Jun, 2018	Chopped
B	03 Jun, 2018	Chopped
C	03 Jun, 2018	Chopped
D	03 Jun, 2018	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6bw8A01	28 Jun, 2018	1.10.437.10	Assigned
6bw8B01	28 Jun, 2018	1.10.437.10	Assigned
6bw8C01	28 Jun, 2018	1.10.437.10	Assigned
6bw8D01	28 Jun, 2018	1.10.437.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1