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PDB 6bw2

PDB Information

PDB6BW2
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Optimization of Potent and Selective Tricyclic Indole Diazepinone Myeloid Cell Leukemia-1 Inhibitors Using Structure-Based Design.
Shaw, S., Bian, Z., Zhao, B., Tarr, J.C., Veerasamy, N., Jeon, K.O., Belmar, J., Arnold, A.L., Fogarty, S.A., Perry, E., Sensintaffar, J.L., Camper, D.V., Rossanese, O.W., Lee, T., Olejniczak, E.T., Fesik, S.W.
J. Med. Chem.
HeaderApoptosis
Released2017-12-14
Resolution2.750
CATH Insert Date03 Jun, 2018

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped
C 03 Jun, 2018 Chopped
D 03 Jun, 2018 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6bw2A01 28 Jun, 2018 1.10.437.10 Assigned
6bw2B01 28 Jun, 2018 1.10.437.10 Assigned
6bw2C01 28 Jun, 2018 1.10.437.10 Assigned
6bw2D01 28 Jun, 2018 1.10.437.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
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