PDB 6bvm

PDB Links
Overview

PDB Information

PDB	6BVM
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling. Abbott, J.R., Hodges, T.R., Daniels, R.N., Patel, P.A., Kennedy, J.P., Howes, J.E., Akan, D.T., Burns, M.C., Sai, J., Sobolik, T., Beesetty, Y., Lee, T., Rossanese, O.W., Phan, J., Waterson, A.G., Fesik, S.W. J. Med. Chem.
Header	Signaling Protein
Released	2017-12-13
Resolution	1.800
CATH Insert Date	16 Dec, 2018

PDB Images (8)

Image of CATH 6bvm

6bvm

PDB 6bvm

Image of CATH 6bvmA

6bvmA

PDB Chain 6bvmA

Image of CATH 6bvmB

6bvmB

PDB Chain 6bvmB

Image of CATH 6bvmC

6bvmC

PDB Chain 6bvmC

Image of CATH 6bvmA00

6bvmA00

CATH Domain 6bvmA00

Image of CATH 6bvmB01

6bvmB01

CATH Domain 6bvmB01

Image of CATH 6bvmB02

6bvmB02

CATH Domain 6bvmB02

Image of CATH 6bvmC00

6bvmC00

CATH Domain 6bvmC00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	16 Dec, 2018	Chopped
B	16 Dec, 2018	Chopped
C	16 Dec, 2018	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6bvmA00	27 Feb, 2019	3.40.50.300	Assigned
6bvmB01	27 Feb, 2019	1.20.870.10	Assigned
6bvmB02	27 Feb, 2019	1.10.840.10	Assigned
6bvmC00	28 Feb, 2019	3.40.50.300	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
Q07889	SOS1_HUMAN	Homo sapiens	Son of sevenless homolog 1
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas