PDB 6bs2

PDB Information

PDB6BS2
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy.
Banerjee, S., Arnst, K.E., Wang, Y., Kumar, G., Deng, S., Yang, L., Li, G.B., Yang, J., White, S.W., Li, W., Miller, D.D.
J. Med. Chem.
HeaderCell Cycle
Released2017-12-01
Resolution2.650
CATH Insert Date06 Jul, 2018

PDB Images (23)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 06 Jul, 2018 Chopped
B 06 Jul, 2018 Chopped
C 06 Jul, 2018 Chopped
D 06 Jul, 2018 Chopped
E 06 Jul, 2018 Chopped
F 06 Jul, 2018 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
6bs2A01 19 Jul, 2018 3.40.50.1440 Assigned
6bs2A02 19 Jul, 2018 3.30.1330.20 Assigned
6bs2A03 19 Jul, 2018 1.10.287.600 Assigned
6bs2B01 19 Jul, 2018 3.40.50.1440 Assigned
6bs2B02 19 Jul, 2018 3.30.1330.20 Assigned
6bs2B03 19 Jul, 2018 1.10.287.600 Assigned
6bs2C01 19 Jul, 2018 3.40.50.1440 Assigned
6bs2C02 19 Jul, 2018 3.30.1330.20 Assigned
6bs2C03 19 Jul, 2018 1.10.287.600 Assigned
6bs2D01 19 Jul, 2018 3.40.50.1440 Assigned
6bs2D02 19 Jul, 2018 3.30.1330.20 Assigned
6bs2D03 19 Jul, 2018 1.10.287.600 Assigned
6bs2E01 19 Jul, 2018 6.10.280.30 Assigned
6bs2F01 19 Jul, 2018 3.40.50.11480 Assigned
6bs2F02 19 Jul, 2018 3.30.470.20 Assigned
6bs2F03 19 Jul, 2018 3.30.1490.20 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q2XVP4 TBA1B_PIG Sus scrofa Tubulin alpha-1B chain
P02554 TBB_PIG Sus scrofa Tubulin beta chain
P63043 STMN4_RAT Rattus norvegicus Stathmin-4
P02554 TBB_PIG Sus scrofa Tubulin beta chain
Q2XVP4 TBA1B_PIG Sus scrofa Tubulin alpha-1B chain
E1BQ43 E1BQ43_CHICK Gallus gallus Uncharacterized protein