PDB 6bqj

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PDB Information

PDB	6BQJ
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Hepatitis C virus
Primary Citation	Potent Inhibitors of Hepatitis C Virus NS3 Protease: Employment of a Difluoromethyl Group as a Hydrogen-Bond Donor. Zheng, B., D'Andrea, S.V., Sun, L.Q., Wang, A.X., Chen, Y., Hrnciar, P., Friborg, J., Falk, P., Hernandez, D., Yu, F., Sheaffer, A.K., Knipe, J.O., Mosure, K., Rajamani, R., Good, A.C., Kish, K., Tredup, J., Klei, H.E., Paruchuri, M., Ng, A., Gao, Q., Rampulla, R.A., Mathur, A., Meanwell, N.A., McPhee, F., Scola, P.M. ACS Med Chem Lett
Header	Hydrolase
Released	2017-11-28
Resolution	1.690
CATH Insert Date	03 Jun, 2018

PDB Images (10)

Image of CATH 6bqj

6bqj

PDB 6bqj

Image of CATH 6bqjA

6bqjA

PDB Chain 6bqjA

Image of CATH 6bqjB

6bqjB

PDB Chain 6bqjB

Image of CATH 6bqjC

6bqjC

PDB Chain 6bqjC

Image of CATH 6bqjA01

6bqjA01

CATH Domain 6bqjA01

Image of CATH 6bqjA02

6bqjA02

CATH Domain 6bqjA02

Image of CATH 6bqjB01

6bqjB01

CATH Domain 6bqjB01

Image of CATH 6bqjB02

6bqjB02

CATH Domain 6bqjB02

Image of CATH 6bqjC01

6bqjC01

CATH Domain 6bqjC01

Image of CATH 6bqjC02

6bqjC02

CATH Domain 6bqjC02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	03 Jun, 2018	Chopped
B	03 Jun, 2018	Chopped
C	03 Jun, 2018	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6bqjA01	28 Jun, 2018	2.40.10.120	Assigned
6bqjA02	28 Jun, 2018	2.40.10.10	Assigned
6bqjB01	28 Jun, 2018	2.40.10.120	Assigned
6bqjB02	28 Jun, 2018	2.40.10.10	Assigned
6bqjC01	28 Jun, 2018	2.40.10.120	Assigned
6bqjC02	28 Jun, 2018	2.40.10.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P27958	POLG_HCVH	Hepatitis C virus (isolate H)	Genome polyprotein
P27958	POLG_HCVH	Hepatitis C virus (isolate H)	Genome polyprotein
P27958	POLG_HCVH	Hepatitis C virus (isolate H)	Genome polyprotein