PDB 6bq0

PDB Information

PDB6BQ0
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation.
McAllister, L.A., Butler, C.R., Mente, S., O'Neil, S.V., Fonseca, K.R., Piro, J.R., Cianfrogna, J.A., Foley, T.L., Gilbert, A.M., Harris, A.R., Helal, C.J., Johnson, D.S., Montgomery, J.I., Nason, D.M., Noell, S., Pandit, J., Rogers, B.N., Samad, T.A., Shaffer, C.L., da Silva, R.G., Uccello, D.P., Webb, D., Brodney, M.A.
J. Med. Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2017-11-27
Resolution2.000
CATH Insert Date03 Jun, 2018

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6bq0A00 28 Jun, 2018 3.40.50.1820 Assigned
6bq0B00 28 Jun, 2018 3.40.50.1820 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q99685 MGLL_HUMAN Homo sapiens Monoglyceride lipase
Q99685 MGLL_HUMAN Homo sapiens Monoglyceride lipase