PDB Information

PDB6BOJ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Memory enhancing effects of BPN14770, an allosteric inhibitor of phosphodiesterase-4D, in wild-type and humanized mice.
Zhang, C., Xu, Y., Chowdhary, A., Fox 3rd., D., Gurney, M.E., Zhang, H.T., Auerbach, B.D., Salvi, R.J., Yang, M., Li, G., O'Donnell, J.M.
Neuropsychopharmacology
HeaderHydrolase/Hydrolase Inhibitor
Released2017-11-20
Resolution1.700
CATH Insert Date26 Aug, 2018

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 26 Aug, 2018 Chopped
B 26 Aug, 2018 Chopped
C 26 Aug, 2018 Chopped
D 26 Aug, 2018 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6bojA00 27 Aug, 2018 1.10.1300.10 Assigned
6bojB00 27 Aug, 2018 1.10.1300.10 Assigned
6bojC00 27 Aug, 2018 1.10.1300.10 Assigned
6bojD00 27 Aug, 2018 1.10.1300.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
Q07343 PDE4B_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4B
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q07343 PDE4B_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4B
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q07343 PDE4B_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4B
Q07343 PDE4B_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4B
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D