PDB 6bkx

PDB Links
Overview

PDB Information

PDB	6BKX
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Novel Modes of Inhibition of Wild-Type Isocitrate Dehydrogenase 1 (IDH1): Direct Covalent Modification of His315. Jakob, C.G., Upadhyay, A.K., Donner, P.L., Nicholl, E., Addo, S.N., Qiu, W., Ling, C., Gopalakrishnan, S.M., Torrent, M., Cepa, S.P., Shanley, J., Shoemaker, A.R., Sun, C.C., Vasudevan, A., Woller, K.R., Shotwell, J.B., Shaw, B., Bian, Z., Hutti, J.E. J. Med. Chem.
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2017-11-09
Resolution	1.650
CATH Insert Date	29 Jul, 2018

PDB Images (7)

Image of CATH 6bkx

6bkx

PDB 6bkx

Image of CATH 6bkxA

6bkxA

PDB Chain 6bkxA

Image of CATH 6bkxB

6bkxB

PDB Chain 6bkxB

Image of CATH 6bkxC

6bkxC

PDB Chain 6bkxC

Image of CATH 6bkxA00

6bkxA00

CATH Domain 6bkxA00

Image of CATH 6bkxB00

6bkxB00

CATH Domain 6bkxB00

Image of CATH 6bkxC00

6bkxC00

CATH Domain 6bkxC00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jul, 2018	Chopped
B	29 Jul, 2018	Chopped
C	29 Jul, 2018	Chopped

CATH Domains (3)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6bkxA00	30 Jul, 2018	3.40.718.10	Assigned
6bkxB00	30 Jul, 2018	3.40.718.10	Assigned
6bkxC00	30 Jul, 2018	3.40.718.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
O75874	IDHC_HUMAN	Homo sapiens	Isocitrate dehydrogenase [NADP] cytoplasmic
O75874	IDHC_HUMAN	Homo sapiens	Isocitrate dehydrogenase [NADP] cytoplasmic
O75874	IDHC_HUMAN	Homo sapiens	Isocitrate dehydrogenase [NADP] cytoplasmic