PDB Information

PDB6BFC
MethodELECTRON MICROSCOPY
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Zhang, Z., Liang, W.G., Bailey, L.J., Tan, Y.Z., Wei, H., Wang, A., Farcasanu, M., Woods, V.A., McCord, L.A., Lee, D., Shang, W., Deprez-Poulain, R., Deprez, B., Liu, D.R., Koide, A., Koide, S., Kossiakoff, A.A., Li, S., Carragher, B., Potter, C.S., Tang, W.J.
Elife
HeaderHydrolase/Hormone
Released2017-10-26
Resolution3.700
CATH Insert Date07 Jan, 2018

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
a 07 Jan, 2018 Rejected
A 07 Jan, 2018 Chopped
b 07 Jan, 2018 Rejected
B 07 Jan, 2018 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
6bfcA01 11 Jan, 2018 3.30.830.10 Assigned
6bfcA02 11 Jan, 2018 3.30.830.10 Assigned
6bfcA03 11 Jan, 2018 3.30.830.10 Assigned
6bfcA04 11 Jan, 2018 3.30.830.10 Assigned
6bfcB01 11 Jan, 2018 3.30.830.10 Assigned
6bfcB02 11 Jan, 2018 3.30.830.10 Assigned
6bfcB03 11 Jan, 2018 3.30.830.10 Assigned
6bfcB04 11 Jan, 2018 3.30.830.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme
P01308 INS_HUMAN Homo sapiens Insulin
P01308 INS_HUMAN Homo sapiens Insulin