PDB 6bb1

PDB Links
Overview

PDB Information

PDB	6BB1
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structure-guided optimization and in vivo activities of hydroxylactone and hydroxylactam Inhibitors of Human Lactate Dehydrogenase Wei, B., Labadie, S.S., Robarge, K., Chen, J., Chen, Z., Corson, L.B., Ding, C.Z., DiPasquale, A.G., Dragovich, P.S., Eigenbrot, C., Evangelista, M., Fauber, B.P., Goa, Z., Ge, H., Hitz, A., Ho, Q., Lai, K.W., Liu, W., Liu, Y., Li, C., Ma, S., Malek, S., O'Brien, T., Pang, J., Peterson, D., Salphati, L., Sideris, S., Ultsch, M., Yen, I., Yue, Q., Zhang, H., Zhou, A., Purkey, H.E. To Be Published
Header	Oxidoreductase/Inhibitor
Released	2017-10-16
Resolution	2.300
CATH Insert Date	16 Dec, 2018

PDB Images (25)

6bb1

PDB 6bb1

6bb1A

PDB Chain 6bb1A

6bb1B

PDB Chain 6bb1B

6bb1C

PDB Chain 6bb1C

6bb1D

PDB Chain 6bb1D

6bb1E

PDB Chain 6bb1E

6bb1F

PDB Chain 6bb1F

6bb1G

PDB Chain 6bb1G

6bb1H

PDB Chain 6bb1H

6bb1A01

CATH Domain 6bb1A01

6bb1A02

CATH Domain 6bb1A02

6bb1B01

CATH Domain 6bb1B01

6bb1B02

CATH Domain 6bb1B02

6bb1C01

CATH Domain 6bb1C01

6bb1C02

CATH Domain 6bb1C02

6bb1D01

CATH Domain 6bb1D01

6bb1D02

CATH Domain 6bb1D02

6bb1E01

CATH Domain 6bb1E01

6bb1E02

CATH Domain 6bb1E02

6bb1F01

CATH Domain 6bb1F01

6bb1F02

CATH Domain 6bb1F02

6bb1G01

CATH Domain 6bb1G01

6bb1G02

CATH Domain 6bb1G02

6bb1H01

CATH Domain 6bb1H01

6bb1H02

CATH Domain 6bb1H02

PDB Prints

PDB Chains (8)

Chain ID	Date inserted into CATH	CATH Status
A	16 Dec, 2018	Chopped
B	16 Dec, 2018	Chopped
C	16 Dec, 2018	Chopped
D	16 Dec, 2018	Chopped
E	16 Dec, 2018	Chopped
F	16 Dec, 2018	Chopped
G	16 Dec, 2018	Chopped
H	16 Dec, 2018	Chopped

CATH Domains (16)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6bb1A01	28 Feb, 2019	3.40.50.720	Assigned
6bb1A02	28 Feb, 2019	3.90.110.10	Assigned
6bb1B01	28 Feb, 2019	3.40.50.720	Assigned
6bb1B02	28 Feb, 2019	3.90.110.10	Assigned
6bb1C01	28 Feb, 2019	3.40.50.720	Assigned
6bb1C02	28 Feb, 2019	3.90.110.10	Assigned
6bb1D01	28 Feb, 2019	3.40.50.720	Assigned
6bb1D02	28 Feb, 2019	3.90.110.10	Assigned
6bb1E01	28 Feb, 2019	3.40.50.720	Assigned
6bb1E02	28 Feb, 2019	3.90.110.10	Assigned
6bb1F01	28 Feb, 2019	3.40.50.720	Assigned
6bb1F02	28 Feb, 2019	3.90.110.10	Assigned
6bb1G01	28 Feb, 2019	3.40.50.720	Assigned
6bb1G02	28 Feb, 2019	3.90.110.10	Assigned
6bb1H01	28 Feb, 2019	3.40.50.720	Assigned
6bb1H02	28 Feb, 2019	3.90.110.10	Assigned

UniProtKB Entries (8)

Accession	Gene ID	Taxon	Description
P00338	LDHA_HUMAN	Homo sapiens	L-lactate dehydrogenase A chain
P00338	LDHA_HUMAN	Homo sapiens	L-lactate dehydrogenase A chain
P00338	LDHA_HUMAN	Homo sapiens	L-lactate dehydrogenase A chain
P00338	LDHA_HUMAN	Homo sapiens	L-lactate dehydrogenase A chain
P00338	LDHA_HUMAN	Homo sapiens	L-lactate dehydrogenase A chain
P00338	LDHA_HUMAN	Homo sapiens	L-lactate dehydrogenase A chain
P00338	LDHA_HUMAN	Homo sapiens	L-lactate dehydrogenase A chain
P00338	LDHA_HUMAN	Homo sapiens	L-lactate dehydrogenase A chain