PDB 6b8u

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Overview

PDB Information

PDB	6B8U
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Imidazo[1,2-a]pyridin-6-yl-benzamide analogs as potent RAF inhibitors. Smith, A., Ni, Z.J., Poon, D., Huang, Z., Chen, Z., Zhang, Q., Tandeske, L., Merritt, H., Shoemaker, K., Chan, J., Kaufman, S., Huh, K., Murray, J., Appleton, B.A., Cowan-Jacob, S.W., Scheufler, C., Kanazawa, T., Jansen, J.M., Stuart, D., Shafer, C.M. Bioorg. Med. Chem. Lett.
Header	Transferase/Transferase Inhibitor
Released	2017-10-09
Resolution	2.680
CATH Insert Date	17 Dec, 2017

PDB Images (7)

Image of CATH 6b8u

6b8u

PDB 6b8u

Image of CATH 6b8uA

6b8uA

PDB Chain 6b8uA

Image of CATH 6b8uB

6b8uB

PDB Chain 6b8uB

Image of CATH 6b8uA01

6b8uA01

CATH Domain 6b8uA01

Image of CATH 6b8uA02

6b8uA02

CATH Domain 6b8uA02

Image of CATH 6b8uB01

6b8uB01

CATH Domain 6b8uB01

Image of CATH 6b8uB02

6b8uB02

CATH Domain 6b8uB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	17 Dec, 2017	Chopped
B	17 Dec, 2017	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6b8uA01	24 Dec, 2017	3.30.200.20	Assigned
6b8uA02	24 Dec, 2017	1.10.510.10	Assigned
6b8uB01	24 Dec, 2017	3.30.200.20	Assigned
6b8uB02	24 Dec, 2017	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf